Good evening. Welcome to The Gut.
The Gut. The hottest dance party in the entire body.
Please have your IDs out.
Oh my God, it's my birthday.
My friends and I are so excited to check out The Gut.
Party! Party! Happy birthday.
You're good to go. Have fun, Chezestix.
Hey! Hello, Vito. Busy night.
Hey, Miss Yogurt. Yeah, it's pretty packed in there.
But come on in. A cultured lady like yourself is always welcome in the good.
You are such a charmer.
Toodle -oo. Hey, girl.
Hey. Seven -day -old shrimp.
You're looking a little rough around the edges.
You sure you're gonna be okay in there?
Yeah, man, I feel good.
Come on, let me in.
What's the worst that could happen?
Fine, I'll let you true.
But don't you make me regret it.
Who, me? Never. Okay, peas and carrots, let's see those IDs.
Uh, hey, Vito, we got a problem inside.
That, uh, seven -day -old shrimp starting fights and breaking stuff.
Ugh, I knew I shouldn't have let him in.
All right, you know what we gotta do.
Evacuate everyone. Everyone?
Everybody. Mom? Yes, honey, what is it?
My tummy hurts. Oh, what happened?
Did you eat something bad?
Uh, just the shrimp I found in my backpack from last week.
I think I'm going to be sick.
Oh, no. Let's get to the bathroom now.
I'm not going to make it.
No, you can make it.
Run, run. All right, everybody out.
And you. What did I do?
I warned you, pal. You're out of here.
That was so gross. Oh, I know, sweetie.
Maybe next time don't eat any backpack shrimp, okay?
Puke. Barf. Vomit. Throw up.
Whatever you call it, we've all eaten something that didn't agree with us, and you know what happens next.
Oops. Feel better, kid.
As I'm sure all yous listening know, when you're feeling sick, your body does all kinds of unpleasant stuff.
Like cough, sneeze, and like our friend here, you might even hurl.
And don't you dare play that sound effect.
But believe it or not, it's not just a virus or the rotten cheese you ate that's causing those nasty symptoms.
It's your immune system.
But what is your immune system?
I don't know. And if your immune system is on your side, then why on earth would it make you do gross stuff like barf up your lunch?
I think I'm going to be sick.
And how does your immune system know what's okay to let inside your body?
And what needs the old heave - Don't say heave.
It's time for another big whiff of science on.
Who's smarted? Who's smarted?
Who's smart? Is it you?
Is it me? Is it science?
Or history? Listen up, everyone.
We make smarting lots of fun on Who's Smarted?
Hey, smarty parents.
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Every time you play outside, eat a sandwich, or give your dog a kiss, your body comes in contact with trillions of germs.
Many are harmless. Some are even good for you.
What? But some can make you sick.
And don't you play that sound effect.
It's your immune system's job to protect you from these outside threats.
Think of your immune system as an internal army dedicated to keeping you healthy.
And just like a medieval castle, your immune system has many lines of defense.
What do you think is your first line of defense against germs?
Is it A. Your mom? I love your mommy.
B. Your mouth? Ah! Or C.
Your skin? Remember to moisturize.
Well, if your first line of defense is like your body's armor, it has to cover the whole outside of your body.
So if you said skin, you're right.
Of course, your mom is also right there helping, too.
No more shrimp for lunch.
But how is your skin like armor?
Don't you get cuts and scrapes all the time?
Ow! Well, it turns out your skin is built like a brick wall.
It's airtight to keep water in, but also really strong to keep bad germs out.
Do not pass go. Which is why, when you do get a cut or a scrape, it's important to clean the wound to prevent germs and infections from getting in.
But otherwise, your skin stands tough against germs.
In fact, your skin works so hard to protect you that skin cells are constantly dying off and being replaced.
We salute you. And do you know what happens to all those dead skin cells?
I don't know. Have you ever noticed dust in your house, either on objects or floating in the air like in a sunbeam?
Well, it's estimated that up to half of the dust in your house is actually dead skin cells.
And it's not just inside your house.
Dead skin makes up about a billion tons of dust in the Earth's atmosphere.
For tomorrow's weather forecast, we're looking at sunny skies with a 100 % chance of dead skin cells?
I'm gonna be sick. Nah, don't worry.
It may sound gross, but we should be thankful to our skin cells for keeping us safe.
But your skin isn't the only soldier on the front lines against harmful germs.
Huh? Other barriers you've evolved to protect you are your hair and your eyelashes, which act like little fly swatters for germs.
But your body's armor isn't perfect, and sometimes bad germs sneak by your first line of defense and start to spread.
And that's when your immune system really gets to work.
To find out how, let's take a trip deep inside your body.
Alright, you two immune cells I need you to keep your eyes peeled Got it, Sarge Hey, you see anything out there?
Nope, we're fine Everything looks clear All over your body Microscopic soldiers called immune cells Are on patrol 24 -7 Keeping an eye out for anything that doesn't belong Hey, what's that?
Incoming! Relax, it's just a toenail Oh, yeah, I knew that.
JK, huh? Every organism that enters your body has a unique molecule on its surface called an antigen.
It's like a fingerprint.
Immune cells are trained to tell the difference between harmless antigens, like food, and dangerous antigens, like flu bugs.
And when they see something dangerous, things get real.
Wait, do you hear something?
Hostile bacteria. They're multiplying.
What do we do? There's too many of them.
Quick, call for backup.
If a bad guy gets through the gates and starts to spread, immune cells sound the alarm.
Reinforcements come streaming to the site of infection to meet the intruders with an all -out assault.
Immune cells assembled.
Charge! Some immune cells gobble up the bacteria.
I got you now, bacteria!
Nom, nom, nom, nom!
Others shoot chemical missiles called antibodies that stop them in their tracks, while other immune cells attach directly to the germs or bacteria, injecting them with toxins until they explode!
As this battle rages, you experience what you know as being sick.
I don't feel well. I think we can all agree, being sick stinks!
You're stuck in bed, no playdates, feeling awful.
But here's the thing, smarty pants.
All of the things that happen to you when you're sick are actually designed to help your immune system make you feel better.
To find out how it works, stick around.
Hi guys, it's Trusty.
Today's episode is brought to you by Squarespace, and I need to tell you about their new design intelligence feature because it's a game changer for anyone who's been putting off creating a website.
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Okay, I want you to think about some of the things that happen to you when you have a cold.
List as many as you can.
Ready? Go. Interesting.
I heard cough, sneeze, sore throat, fever.
I'm burning up. chills, body aches, ow, runny nose, diarrhea, throwing up, the desire to watch cartoons.
Well, except for watching cartoons, all of those responses are a direct result of your immune system working to protect you.
For example, when you have a stomach bug, you'll either throw up or get diarrhea.
I know, I know it's gross to be spewing nasty fluids.
Don't you dare play that sound effect.
But both of those are ways your immune system ejects germs from your body.
Because within those nasty fluids are the bugs that made you sick.
What about a fever?
A fever is when your body temperature rises.
Obviously, this is no picnic for you with chills and body aches, but it's even less fun for germs.
When your body heats up, it actually stuns harmful bacteria and makes them move slowly, buying your immune system more time to knock him out.
And what do you do most when you're sick?
Play soccer? Goal! Walk the dog?
Or sleep? Chances are you just want to sleep.
And that's no coincidence.
Sleep gives your whole body a rest.
Laying in your bed sleeping, your body doesn't have to worry about thinking or moving or eating.
And it can devote all of its energy to your immune system to kick your infection's butt.
So, the best way to recover from illness is to rest up and drink lots of fluids.
And why fluids? Because fluids help your immune system flush out toxins.
And before you know it, your body's army will have you back on your feet.
That's the last of them, we're clear Yay, we did it But wait, wait, I haven't even told you the coolest thing your immune system can do Your immune system isn't just a master at destroying bad germs It also has a super memory Once your body fights off a bad bacteria or virus Chances are you'll never
get sick from that exact strain again Whoa If the same bad guy tries to get in again Your immune system will immediately recognize it And turn it away before it has a chance to do any damage all right folks ids please all right folks let's see those ids hey sounds like a fun party in there gonna let
me in oh no you don't old shrimp you're not getting in this time why what did i do what did i do you just had to play that sound effect didn't you A big double shout out to our awesome fans Caden and Kaylee in Westminster, Maryland.
We're so glad you love listening to Who Smarted.
Today's episode, Immune System, was written by Dan Bromfield and voiced by Dan Bromfield, Gia Davis, Adam Tex Davis, Jason Williams, Chris Van Cleef, Kim Davis, Sydney Blumenfeld, April Cantor, featuring Les Nessman as the weatherman, and yours truly, Jerry Colber.
Technical direction and sound design by Josh Hahn.
Who Smarted was recorded and mixed at the Relic Room Studio.
Theme song by Brian Suarez.
Lyrics written and performed by Adam Tex -Davis.
Who Smarted was created and produced by Adam Tex -Davis and Jerry Kolber.
This has been an Atomic Entertainment production.