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Hey, Wowzer fans, Mindy here.
And before we start the show, I gotta let you know that this November, with a special new episode featuring our friends at Circle Round and Terrestrials on Radiolab for Kids,
And don't miss when Elmo from Sesame Street stops by Wow in the World to make us all belly laugh on November 24th.
Oh, but that's not all, Reg.
On December 1st, we are sharing our 250th episode of Wow in the World with all of you.
We think this one is going to be music to your ears.
Literally.
Did I mention it's a musical?
And if you're a member of the World Organization of Wowzers...
Oh boy, do I have a surprise for you.
You can listen to our 250th episode early with me and other members from around the world on Saturday, November 22nd, at 7 pm.
Eastern.
That's right, we are throwing another listening party.
Join us as we dance along to our new songs.
React to the episode with other members in the chat and more.
Grownups.
If you want your wowzer to join this members-only listening party, you can sign up to become a member today at Tinkercastcom.
Slash wow.
Already a member?
Well, you can find the link and password to join the event when you sign in at Tinkercastcom.
Slash wow.
That's it.
It's going to be a November to remember.
But for now, let's get on with the show.
Woo!
A beautiful day for a hike.
My cantina's full, my trekking poles are polished, and my feet are itchy to get started.
I hope Mindy is as excited for this trek as I am.
Mindy?
Hello?
Hey, Ron?
Mindy, where are you?
I'm out in the back.
Come on through.
I kind of got my hands full right now.
All right.
Thanks.
Hey, Guy Razzi!
Mindy, what's going on out here?
No time to explain, Guy Raz.
Here, put on that bee suit over there.
These buzzers are in a very stingy mood today.
Okay, if you say so, Mindy.
Let me just get this.
There we go.
Wait a minute, Mindy.
Why am I wearing this?
And what is this?
Oh, it's a bee suit, Guy Raz.
I just told you that.
Mindy, a bee suit is actually a layer of protective clothing to protect you when handling bees, not a suit that makes you look like a giant bee.
Oh, that would explain why I'm in so much pain right now.
Stop it.
Well, what are you even doing with a bee colony back here, Mindy?
I mean, we're supposed to go on a hike today.
Didn't you get my message in a bottle?
Message in a bottle?
No.
Sorry, Guy Raz.
I can't make the hike today.
There's a doctor's appointment that I can't get out of.
A doctor's appointment?
For what?
A vaccine.
Well, what sort of vaccination?
American Foulbrood.
American Foulbrood?
I've never heard of that disease before.
Well, that's because it's not a human disease, Guy Raz.
Not a human disease?
Nope.
It only affects bees.
Oh.
Wait a minute here, Mindy.
Who is this doctor's appointment for?
Her.
Ow!
Uh, her who?
Her majesty.
What?
The Queen Bee guy, Roz.
That's who I'm trying to get out of this hive here.
Ow!
Come on, you little buzzies.
Chill out.
I'll bring her back.
Come on.
Wait a minute.
You're taking your Queen Bee to get a vaccine?
Yeah.
Here.
Hold on to this hive for a second.
Huh?
Catch!
Ow!
Don't worry, Guy Raz.
I'm going to make this real quick.
Fine.
I can see her right there at the back of the hive.
I see you.
Be quick, Mindy.
This bee suit does nothing to protect me.
Oops, sorry.
Nothing.
I've got my tweezers all ready, Guy Raz.
Just hold that hive still.
I'm trying.
Here, queenie, queenie, queenie, queenie, queenie.
I see you.
Quickly, Mindy.
I got it.
Finally!
Okay, you can put the hive down now, Guy Raz.
Now, just got to put her in her little travel case here.
There you go, Queenie.
Right at home.
Thanks for your help, Guy Raz.
Don't mention it.
So, you want to come to the vet with us?
Well, I guess my schedule did just clear up.
Oh, how convenient.
Come on, we're already late.
To the ice cream truck!
Hold up, Mindy.
It's really hard to run in this bee suit.
Okay, unlocking the ice cream truck.
All right.
Uh, I'm not sure I'm gonna fit into the truck with this suit on, Mindy.
Well, not with that attitude, you won't.
Here, let me give you a little push and a shove.
Easy there.
Easy.
Don't you mean... Easy?
Mindy!
Ow.
There we go.
All right, Guy Raz.
Here, you hold on to Queenie for me.
Okay.
Hi there, Queenie.
Who's a good bee?
You are.
Oh, she loves when you talk to her all cute like that.
All buckled in?
No.
Then you better hold on to something, because here we go!
Mindy, slow down.
I am a live bee on my lap.
Sorry, got a little carried away there.
So, Mindy, what exactly is Queenie getting vaccinated for again?
Oh, it's a bee disease or a...
Bee-zies, as I like to call it.
It's called American Foulbrood and it's causing some serious problems in beehives all over the world right now.
Huh, well, what does it do?
Well, I could tell you.
But you'd rather show me?
What?
No!
I'm going to play you this podcast where I first heard about it.
Oh.
Here, take the wheel.
Ah, Mindy, you know how dangerous it is when you remove the steering wheel like that.
Okay, and I'm just going to borrow your guy phone here to pull up this podcast.
Now where is that podcast?
Uh, 10 flappier how i quilt this, my favorite burger.
Oh, here it is buzz bead and play hello and welcome back to buzz bead, a podcast all about what's a buzz in the world of our honey making friends.
Huh, this guy sounds kind of familiar.
He's just getting to the part about the bee-zees.
Today we take a look at American Foulbrood, a devastating disease causing havoc in bee hives all over the planet.
This particular disease is carried back to the hive by worker bees.
Once inside the hive, it spreads rapidly, killing off the infant larvae.
Oh, no.
That's so sad.
I know.
And it gets worse.
As the larvae are removed from the hive, there are no young left to take over from the old.
The hive grows weaker and eventually dies.
Yikes.
Yikes.
Right, Guy Raz?
And the worst part is that it doesn't affect just one hive.
This disease can jump from hive to hive, killing off whole regions of bees.
But they have a vaccine to help prevent this now, right?
I mean, that's why we're taking Queenie here to the vet.
Yeah, these two scientists, Heli Samella and Dahlia Freitig, helped make the first ever vaccine.
The vaccine that protects them against the American foul brood disease?
That's the one.
Okay, but why are you just bringing the queen along, Mindy?
I mean, don't you want all your bees to be protected against this disease?
Of course, Guy Raz.
I love all of my bees equally.
Well, then why not vaccinate all of them?
Good question, Guy Raz.
And the answer lies in how the bees' immune systems work.
Okay.
And I'll tell you all about it once we're inside.
Inside where?
The vet.
Look, we're here.
Oh, right.
Ta-da!
Mindy, a little help here, please.
Oh, right.
Sorry.
I got you, buddy.
Man, this bee suit is really bulky.
Come on.
Come on.
There you go.
Okay.
Locking up The ice cream truck here?
Thanks for looking after Queenie Guyraz.
No problem.
Are you ready for your little doctor's visit, Queenie?
It's not going to be that bad.
Come on.
Let's go inside.
Hi there.
Welcome to Vet Well Soon.
Do you have an appointment today?
Yes, I do.
I am here for the American Foulbrood vaccination.
Not me, obviously.
She is.
This is Queenie.
Well, hello there, Queenie.
Oh, it's very nice to meet you.
Let me just get you signed in here.
There.
You're all set.
You can take a seat over there, and the doctor will call you when it's your turn.
After you, Guy Raz.
So Mindy, what did you mean before when you said that bees' immune systems were different to ours?
Oh, right, yeah.
So you know how our human body's immune systems work?
Kind of like taking a little picture every time a new disease enters our body?
Yeah.
And how it then files that picture away in its memory banks so that the next time the disease enters our body it can look up that file and say hey, I know you and I know how to fight you off too.
Yeah, and so when we get vaccines, we're often getting a tiny little bit of the disease that we're protecting ourselves against.
Not enough of the disease to actually make us sick, but enough for our immune system to take a look at it and get that picture.
Exactly.
It's sort of like a practice run.
They take these pictures and then file them away in their How to Fight Off Diseases database.
Right.
Well, here's the thing, Guy Raz.
Bees do not have that database in their body's immune systems.
Huh.
Well, then how do they build up immunity to disease?
They do it through their babies.
You mean their offspring?
Yeah.
So if the mother is immune or protected from a certain disease, she then passes that protection on to all of her little babies.
Which is why you're bringing just Queenie along to the vet.
Because the queen is the only bee in the beehive that produces babies.
Babies or offspring.
Ah, you're picking up what I'm putting down, Guy Raz.
So, uh, how does Queenie deal with needles, Mindy?
She won't be getting her vaccine through a needle, Guy Raz.
She won't?
Nope.
This vaccine is administered through... Wait for it.
Okay.
Wait for it.
Uh, no, I'm not doing this.
Wait for it.
Mindy!
Jelly!
Jelly?
Yeah.
Royal jelly.
She gets the vaccine through royal jelly?
That sounds a lot better than needles.
Mindy and Queenie?
Oh, that's us.
Come on, Guy Raz.
Right behind you, Mindy.
Right through here.
Thank you very much.
And close the door, please, if you wouldn't mind.
Closing the door?
Okay, let's take a look at your chart.
You're here for the American Foulbrood vaccine, is that right?
That's right.
Excellent.
I believe I have some of that royal jelly here in the fridge.
What?
In the fridge?
Yeah.
Jelly goes in the fridge.
Everyone knows that.
Oh, right.
Let's see.
No, that's ketchup.
Oh, boy.
Oh, no.
How long has this been here?
The American Foulbrood vaccine.
And here you are.
Ooh, looks delicious.
It's not.
Don't mind if I... Indy, stop.
Sorry.
All right, little Queenie.
Time to come out of your carrier now.
Come on.
Come on now.
Sorry.
I think she's a little nervous.
Not to worry.
Happens all the time.
I'll step out and give you some privacy.
Come on, Queenie.
Look at this jelly.
It's all for you.
Yum, yum, yum.
So, Mindy, the vaccine is in that?
That's right, Guy Raz.
Right there in the jelly.
Wow.
See, in the real world, the vaccine would be placed in flowers that the bees get their nectar from.
Then, once the bee goes back to the hive, the worker bees would turn that nectar and the vaccine inside of it into royal jelly for the queen to dine on.
A meal fit for a queen.
Yep.
Hear that, Queenie?
Even Guy... wants you to eat this jelly.
Look, Mindy, I think she's coming out.
That's it, Queenie.
Come on.
There she goes.
She's doing it, Mindy.
She's eating the jelly.
Yay!
Good job, Queenie.
So what's next for this vaccine, Mindy?
Well, the Department of Agriculture just approved its use in the US.
So the next step is to get it out to all of the bee farms all across the country.
Wow, so they're ready to roll it out?
That's right.
It's the first time a vaccine for insects has been approved in the U.S.
That's pretty groundbreaking, Mindy.
Yeah, I know.
And the hope for these scientists is that over time we'll be able to completely eliminate American foulbrood from the entire world bee population.
And who knows, Mindy?
Maybe this will lead to other vaccines for other insects and other diseases.
That's the hope, Guy Raz.
It feels like this could be just the beginning.
Yay!
You did it, Queenie!
Good job!
Now it's time to get you back in your carrier.
Come on here.
Come on.
Get back inside.
Uh, I don't think she wants to go back inside, Mindy.
Well, she doesn't have much of a choice, Guy Raz.
Sorry, Queenie.
It's tweezer time.
Come on.
She's flying all over the room, Mindy.
Don't worry, Guy Raz.
I got this.
Come on, Queenie.
Come on.
So close.
Come here.
Mindy.
I'm just trying to get you.
My office.
Got her.
Unbelievable.
Loud in the World will be right back.
This message is for you.
Our Wow in the World toys help your wowzer learn about their world through play.
Plus, you can hear exclusive audio content from me and Guy Raz to help your wowzer discover even more wows.
Grownups.
Give the gift of wow and wonder this holiday season with our latest Wow in the World toys designed with your curious wowzer in mind.
You can shop our Wow in the World toys at Tinkercast.com slash toys.
That's Tinkercast.com slash toys.
Hi, thanks for calling Wow in the World.
After the beep, get ready to record.
Hi, Mindy and girls.
My name is Sarah.
I live in Fremont, California.
I'm 10 years old.
My Wow in the World is that at one point, purple dye was more valuable than gold.
How crazy is that?
Say hi to Grandma G-Force.
Dennis.
Ahoy there.
Reggie and Thomas Fingerling.
I love your show.
Bye.
Hi, Mindy and guys.
My name is Mia and I'm from Irving, Texas.
And my wow in the world is that the Great Wall of China is made out of stone, wood bricks and sticky rice.
Say hi to Static Man for me. can digest a frog.
Isn't that crazy?
Say hi to the annoying Dennis.
Howdy.
Reggie and Grandma G-Force me.
Oh, snap.
Bye.
Hi, Mindy and Guy Raz.
I'm Raina from Burning, California, and I'm 10.
My wow in the world is that electric eels are closely related to carp and catfish.
Say hi to Grandma G-Force and Dennis for me.
Booyah!
Huzzah!
Bye.
Hi, Mindy and Guy Raz.
My name is Eli from Helena, Alabama.
Did you know that a wildebeest is actually a type of antelope?
Isn't that Bunker Bob?
Say hi to Reggie.
Alice the cat.
Dennis.
Hi there.
Bucky the horse.
And Static Man.
Ha ha ha ha ha!
They are born pink.
They are born gray.
But because of their diet of shrimp and algae, their feathers slowly turn pink.
Say hi to Grandma G's horse, Dennis, and Reggie for me.
And my wow in the world is that 18 Egyptians made toothpaste.
Say hi to Reggie for me and make sure that Dennis doesn't bother you anymore.
What?
Bye.
Hello, Mindy and Guy Ross.
My name is Samuel and I'm from Miami, Florida.
And my wow in the world is that it takes a sloth 31 days to digest one leaf.
Bye, Mindy and Guy Ross.
I loved your show.
Say hi to everyone for me.
Cool, dude.
Bye.
Wow in the World is written by Mindy Thomas and Tom Van Kalken with help from me, Guy Raz.
Original sound design and music editing is done by Tyler Thole with help from our supervising producer, Jed Anderson.
You can also hear Jed Anderson in the voices of Dennis Thomas Fingerling, Reggie and many of the other silly characters you hear on our show.
Jessica Bode keeps our facts straight as our fact checker and Meredith Halpern-Ranzer powers the wow at Tinkercast.
Our theme song was composed and performed by three-time Grammy nominees, The Pop-Ups.
Find them at thepopups.com.
Special thanks to Steph Sosa, Henry Moskal, Ruth Morrison, Rebecca Caban, Kit Ballinger, Sana Ali-Mohamed, Anna Zygorski and all of the other tinkerers at Tinkercast HQ.
To keep the wows rolling, visit us at Tinkercast.com.
There you can learn more about becoming an official member of the World Organization of Wowsers.
Learn about upcoming events, shop our wow shop, find our best-selling books and learn about all of our other amazing podcasts from Tinkercast.
Grownups.
You can follow Wow in the World on Facebook, Instagram and Twitter at at WowInTheWorld, and our email address is hello at Tinkercastcom.
And if you're a kid with a big wow to share with us, call us at 1-888-7-WOW-WOW for a chance to be featured at the end of our show or an upcoming episode of Two What's and a Wow.
Thanks again for listening, and until next time, be fun wowing!
Wow!
The world was made by Tinkercast and sent to you by Wondery.
