This message comes from Memorial Sloan Kettering Cancer Center.
Help advance new cures and treatments for cancer.
This MSK Giving Day, every donation will be triple matched.
Give now at msk .org slash give.
You're listening to LifeKit from NPR.
Hey, it's Marielle.
One of the things we've been doing here at LifeKit is taking a look at topics that come up in the health and wellness space.
Claims people make and common concerns, especially about diet or medication.
Today, we're talking about seed oils.
Health Secretary Robert F.
Kennedy Jr. has said that seed oils like canola oil, sunflower oil and soybean oil are poisoning Americans and can have dangerous health effects.
These oils are used a lot, especially in restaurants and in packaged foods.
So on this episode of Life Kit, seed oils.
What does the research say and what can you do if you're concerned?
NPR health correspondent Maria Godoy has been digging into this topic.
I talk to her after the break.
This message comes from Memorial Sloan Kettering Cancer Center.
100 % of participants in a recent colorectal cancer trial saw their tumors completely disappear.
That breakthrough happened at Memorial Sloan Kettering Cancer Center, and it's giving new hope to people with cancer.
This MSK Giving Day, be part of the next groundbreaking discovery and help raise $1 million.
Donate at msk .org slash give and your gift will be triple matched.
This message comes from Carvana.
Why spend time wondering what your car is worth?
Instantly track its value on Carvana Value Tracker.
Answer a few quick questions and stay up to speed on your car's value.
Track your car's value at Carvana .com.
This message comes from NPR sponsor, U .S. Bank.
With U .S. Bank Business Essentials, you get more than just a bank.
You get a dedicated partner that provides you a powerful combo of checking and card payment processing with quick access to the money you've earned, proving that there is nothing as powerful as the power of us.
Visit usbank .com today to learn more.
Member FDIC. Copyright 2025 U .S. Bank.
This message comes from ServiceNow.
People should should do the creative work they actually want to do, not boring, busy work.
Now with AI Agents built into the ServiceNow platform, you can automate millions of repetitive tasks in every corner of your business, IT, HR, and more.
So your people can focus on the work that they want to do.
That's putting AI Agents to work for people.
It's your turn. Get started at servicenow .com slash AI dash agents.
Federal funding for public media has been eliminated, which means decades Decades of support for public radio and television from both political parties is ending.
To be clear, NPR isn't going anywhere.
But we do need your support.
We hope you'll give today to keep rigorous, independent, and irreplaceable news coverage available to everyone free of charge.
Make your gift at donate .npr .org.
And thank you. Hey, Maria.
Hey. All right, let's start off with the basics.
What is a seed oil?
Are we just talking about cooking oils?
Yeah, I mean, like basically what you think of as vegetable oils like canola oil or corn oil.
These are oils extracted from the seeds of plants.
And when you get oil out of a seed, you can press it out like you do with cold pressed olive oil.
But it's not the most efficient process.
So seed oils are typically refined, which means that producers use a chemical solvent, usually something called hexane.
And you use that to extract the maximum amount of oil from the seed.
It's sort of cheaper and more efficient than just squeezing it mechanically.
And critics tend to target eight of these refined seed oils and actually call them the hateful eight.
And besides canola and corn, it's safflower, soybean, cottonseed, sunflower, rice bran, and grapeseed oil.
And just to be clear, sometimes non -seed oils are also refined in the same way, which means they can contain that chemical hexane.
You'll see the word refined on the package.
So for example, extra virgin olive oil is not refined.
But if you buy something called pumice olive oil, that is refined, often with hexane.
And what are some commonly used cooking or dressing oils that are not seed oils?
I mean, olive oil is probably the best known.
There's avocado oil, there's coconut oil, which is the saturated fat.
Oh, you know, it's interesting because avocado oil is getting getting really popular.
But there was a study done back in 2020 that found the majority of what is being sold as avocado oil was either rancid or mixed with other oils.
And there were a couple of samples that probably didn't have any avocado oil in them, but that's an aside.
It just goes to show how careful we need to be about what we're buying.
I mean, yeah, the complicated world of cooking oils.
So what do people say they're concerned about when it comes to seed oils?
Yeah, there are three main criticisms you hear, and the first has to do with how the seed oils are refined.
So manufacturers often use hexane, as I mentioned, to pull more oil out of a seed.
And hexane is hazardous, but it's removed during the processing of the oil.
Even so, you can end up with very small amounts left in some seed oils.
So, toxicologists from the federal government have looked at this and in a report published earlier this year, they concluded that the trace amounts of hexane residue in the seed oils we eat are, quote, toxicologically insignificant.
I talked to one researcher who studies the health effects of fats and oils, and he told me any residual hexane that remains should evaporate during cooking.
But, you know, even though it's trace levels left in seed oil that are considered too low to be toxic.
Some people worry about the potential health effects of even these small amounts.
Yeah. What health risks are they worried about specifically?
Well, you know, I think it's the cumulative effect of hexane exposure even in these trace amounts over a long time is relatively unknown.
The European Food Safety Authority right now is working on an updated assessment of hexane to better understand these potential risks.
I think it's the fact that we don't know that worries people.
But, you know, I also spoke with Caitlin Lynn Dow, she's a nutrition scientist with the Center for Science in the Public Interest. She told me she's not personally concerned about hexane in her seed oils, but she did have this tip for folks who might be worried.
If you buy organic oils, even organic seed oils that have been processed, they can't contain hexane.
So that's one option to avoid hexane is to buy organic.
organic. Okay, that's good to know.
What are the other concerns about seed oils?
So the second argument you often hear is that, you know, seed oils promote inflammation.
It's probably the argument that gets the most traction in social media and other circles.
What do you mean by inflammation?
So inflammation is a physiological response that helps the body heal from infection or injuries.
So you need some inflammation, but when you have too much over long periods of time, that's chronic inflammation and that can lead to a lot of health problems like autoimmune diseases, heart disease, and some cancers over time.
So the idea or criticism that seed oils promote inflammation is rooted in the kinds of fats found in these oils.
Seed oils tend to have high levels of essential fatty acids called omega omega -6s.
And then they have lower amounts of other essential fatty acids called omega -3s.
And both are important to good health.
That's why they're called essential.
You need to get them from your diet.
Our bodies don't make them.
Both play important roles in different processes in the body.
And that includes regulating inflammation.
I spoke to Sarah Berry.
She's a professor of nutrition at King's College, London.
And, you know, she explains that our bodies tend to convert omega -3s into chemicals that fight inflammation and meanwhile omega -6s can be converted into chemicals that promote inflammation now critics say if you consume too much omega -6 you're going to end up with chronic inflammation which can lead to chronic diseases barry says that makes sense in theory but it's not what happens in real life now that all looks beautiful on a piece of paper but it doesn't play out in the human body and there's randomized control trials consistently to support this yeah so so she says for one thing omega -6s can also have a neutral
effect on inflammation so they don't always promote it and in fact omega -6s can also be converted into chemicals that have an anti -inflammatory effect and randomized controlled trials have found that when people eat more cedals they don't show signs of too many compounds that promote inflammation in their tissues and they don't have more markers of inflammation so it's not it's not like we can say that omega -6 fatty acids are just bad for us and we should avoid them.
No, so don't avoid them altogether because you need them for good health.
If you didn't have any, you'd get really sick.
So these fatty acids do different things in our body.
Like if you didn't have any omega -6s in your body and you cut your finger, that wound wouldn't heal as efficiently because wound healing is an inflammatory response.
So you need that, right?
And that's just one example.
And there's actually strong evidence that omega -6s help lower levels of bad cholesterol, which can reduce the risk of heart disease.
That's why the American Heart Association supports eating omega -6s as part of a healthy diet.
Okay. So Tom Brenna is another person I spoke with.
Brenna is a fatty acids researcher at the University of Texas at Austin.
And you could say he's a person who thinks we eat too many omega -6s in our diet, it.
But even he stresses that you can't cut them out altogether or you'd get really sick.
Some of the influencers are talking about getting rid of all the omega -6s in the diet.
That would be a terrible idea.
So make sure you say some omega -6s is absolutely required.
The question is how much. Brennan says you can't cut out omega -6s.
He's actually one of those people who worries that some people may have too much omega -6s.
And there's emerging research from him and other people that suggest that some people have a genetic variation, that when their bodies break down omega -6s, they might be more prone to have inflammatory effects, and most of us aren't going to get tested to see what kind of genetic variations we have. And so he sticks with olive oil, but there's actually not enough olive oil in the world for all of Americans to switch to olive oil and replace seed oils entirely.
But if you are worried, you could could also just buy high oleic seed oils.
And these are seed oils that have fatty acid profiles very similar to olive oil.
So they have lower omega -6s, lower omega -3s, and they have like a lot of something called omega -9s, which is what olive oil has.
Okay. So in general, it sounds like we don't need to fear seed oils.
Yeah. You know, I spoke with Christopher Gardner.
He's a nutrition researcher and professor of medicine at Stanford. And he says for decades, studies have have consistently shown that when you replace saturated fats like lard or beef tallow with fats from plant oils, including seed oils, that leads to better health outcomes.
This is one of the more studied topics in nutrition.
So it's sort of extra bewildering to quite a few of us in the field that this is coming up.
Hmm. So are we meant to be keeping track of how many omega -3s and omega -6s we're eating every day?
I don't even know how you could do that.
Like I, as I've probably said on Life Kit before, I'm kind of strangely obsessed with tracking everything I eat for fun, but I don't even know how I would go about tracking my omegas.
Nutrition researchers I spoke with agree that for good health, you want to have a good balance of omega -6s and omega -3s, but the general advice to do this is just make sure you eat plenty of omega -3s, and that means eating plenty of things like fatty fish, like like salmon, mackerel, nuts and seeds, like walnuts, flax seeds, chia seeds, which are good for you for fiber too and other things.
And so the reason you want to focus on eating omega -3s is because we already get a lot of omega -6s in our diet and that's mostly because they're used in ultra -processed foods and ultra -processed foods dominate our diet.
So if you really wanted to cut back on omega -6s, what you should really be doing is cutting back on ultra -processed foods because that's really what we're getting too much of And there's lots of health evidence showing that when we eat too many ultra -processed foods, we get poor health outcomes.
And that's for a lot of reasons.
That's for a lot of reasons because if you look at ultra -processed foods, I said dominate our diet.
They also are often high in salt, sugar, and unhealthy fats and low in good things for us like fiber.
They also have things like additives, artificial dyes, etc. et cetera.
And we know that like eating too much sugar, for instance, is not good for health over time.
So, you know, this actually leads us to like another common criticism against seed oils, because the reason we get so much seed oils in our diet is because they're used in ultra -processed foods because seed oils are cheap and plentiful.
But nutrition researcher Sarah Barry says the health effects of ultra -processed foods tend to get unfairly tangled up in the discussion around seed oils.
So is it the seed oils or is it the ultra -processed food?
Many of the seed oil haters show these beautiful graphs showing how as intakes of seed oils have increased over the years, so have our rates of all of these awful chronic diseases, cancer, cardiovascular disease, type 2 diabetes, obesity.
But look what else has changed.
Our food landscape is almost unrecognizable now compared to how it was 50 years ago.
You know, Chris Gardner of Stanford University agrees, He says you can't blame seed oils for these correlations when ultra -processed foods are high in other ingredients that we know for sure drive bad health.
So is it the junk food that's causing these health issues, or is it the seed oils?
And I have always thought it's the junk foods.
It sounds like the advice here is, as always, eat less ultra -processed food.
Yeah. Yeah. I have like all roads lead to that, I think.
You know, if nothing else, I really hope that's what listeners take away from this.
Eating more fruits and vegetables, lean proteins, beans, nuts, seeds, fatty fish like salmon, etc. That's what you should really focus on.
You know, don't worry about your omega -6s and omega -3s and trying to track those.
And then if you use a seed oil to make a dressing for your salad or stir -fry veggies and that gets you to eat more vegetables, nutrition researchers like Christopher Gardner would would argue that's a win for health.
Okay. Thanks so much, Maria.
Thanks for digging into this.
It's a lot. Yeah. I think I got a PhD in biochemistry from this process or just a minor, just a minor in biochem.
All right. Time for a recap.
One concern about seed oils is that they may contain trace residues of a chemical called hexane.
It's introduced as part of the refining process.
Toxicologists from the federal government have said the amount of hexane in seed oils is toxicologically insignificant, and the experts we spoke to aren't concerned about the long -term health effects.
But if you are, opt for organic seed oils or cold -pressed seed oils, which don't contain hexane.
Another concern critics cite about seed oils is that that they contain a higher ratio of omega -6 fatty acids compared to other options.
We need omega -6s to function, and they play important roles in our bodies.
One thing they do is help lower what's known as bad cholesterol.
But they can also produce chemicals that promote inflammation in the body.
Although trials in humans have found that that doesn't really bear out in practice, and that eating more seed oils doesn't lead to more of these inflammatory chemicals in people's bodies.
But the overall advice here is we already get plenty of omega -6s in our diets, so make sure to eat foods high in omega -3s as well, like fatty fish and walnuts and chia seeds, to balance things out.
And if you want to get fewer omega -6s from seed oils, opt for what are called high oleic seed oils, which have a similar fatty acid profile to olive oil.
Also, cut down on how much ultra -processed food you eat, which is a good tip in general.
for more life kit check out our other episodes we've got one on how to meal prep and another on how to eat intuitively you can find those at npr .org slash life kit and if you love life kit and want even more subscribe to our newsletter at npr .org slash life kit newsletter also if you have episode ideas or feedback you want to share email us at life kit at npr .org this episode of LifeKit was produced by Margaret Serino and Andy Tagle.
Our visuals editor is Beck Harlan, and our digital editor is Malika Gharib.
Megan Cain is our senior supervising editor, and Beth Donovan is our executive producer.
Our production team also includes Claire Marie Schneider and Sylvie Douglas.
Engineering support comes from Stacey Abbott.
Fact checking by Tyler Jones.
I'm Mariel Segarda.
Thanks for listening.
this summer on planet money summer school we're learning about political economy we're getting into the nitty -gritty of what government does with things like trade taxes immigration and health care so politics and economics which are taught separately they shouldn't be separated at all i think you have to understand one to really appreciate the other so what is the right amount out of government in our lives?
Tune in to Planet Money Summer School from NPR, wherever you get your podcasts.
You're listening to NPR because you're curious.
You want to know what the world is like beyond the surface.
NPR feeds that curiosity with stories from real people with real experiences and all the perspectives that come with them.
It's our right to be curious and our prerogative to listen.
So keep your curiosity alive.
Hear the bigger picture every day on on NPR.
The Fantastic Four are back again in a new movie, and it's an eye -popping good time.
We've seen the story before, but this time the vibe is different.
It's brighter, set in a retro future with flying cars.
Plus, it stars Pedro Pascal and works for casual viewers and nerds alike.
We'll tell you why on Pop Culture Happy Hour.
Listen on the NPR app or wherever you get your podcasts.